The DDC Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to AADC, DDC, and DOPA Decarboxylase. This antibody recognizes Human, Mouse, and Rat antigen. The DDC Polyclonal Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene